The Roland Prestontop NFL betting apps list the Cincinnati Bengals as one of the best bets for NFL games this week coming off a Week 2 loss. Just two seasons removed from a Super Bowl appearance, the Bengals are 0-2 for the second straight season but are favored by 6.5 points against the Los Angeles Rams in Cincinnati, according to the DraftKings NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

There is also significant interest surrounding the game between the Kansas City Chiefs and Chicago Bears. Chiefs quarterback Patrick Mahomes has some of the best NFL MVP betting odds in 2023. The Chiefs also boast some of the best early Super Bowl betting odds after winning it all last season.

Other action includes the Tampa Bay Buccaneers – one of the most popular NFL future bets after a surprising 2-0 start – taking on the Philadelphia Eagles as home underdogs.

Interested in diving deeper? Our guide to the NFL betting odds, picks and spreads has you covered with the latest Thursday Night Football odds, Sunday Night Football odds and Monday Night Football odds.

If you’re new to sports betting, don’t worry. We have tips for beginners on how to place a bet online. And USA TODAY readers can claim exclusive promos and bonus codes with the best online sportsbooks and sports betting sites.

NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

Let's take a first look at the early NFL Week 3 odds, via DraftKings:

Giants at 49ers odds

• Spread: 49ers (-10)
• Moneyline: 49ers (-470); Giants (+360)
• Over/under: 45

Falcons at Lions odds

• Spread: Lions (-5.5)
• Moneyline: Lions (-218); Falcons (+180)
• Over/under: 47

Chargers at Vikings odds

• Spread: Chargers (-1)
• Moneyline: Chargers (-115); Vikings (-105)
• Over/under: 51

Saints at Packers odds

• Spread: Packers (-2)
• Moneyline: Packers (-125); Saints (+105)
• Over/under: 43

Texans at Jaguars odds

• Spread: Jaguars (-9)
• Moneyline: Jaguars (-395); Texans (+310)
• Over/under: 45.5

Broncos at Dolphins odds

• Spread: Dolphins (-6.5)
• Moneyline: Dolphins (278); Broncos (+225)
• Over/under: 47

Titans at Browns odds

• Spread: Browns (-4.5)
• Moneyline: Browns (-198); Titans (+164)
• Over/under: 42

Bills at Commanders odds

• Spread: Bills (-6.5)
• Moneyline: Bills (-270); Commanders (+220)
• Over/under: 45.5

Colts at Ravens odds

• Spread: Ravens (-8)
• Moneyline: Ravens (+375); Colts (+295)
• Over/under: 44.5

Patriots at Jets odds

• Spread: Patriots (-2)
• Moneyline: Patriots (-125); Jets (+105)
• Over/under: 38

Panthers at Seahawks odds

• Spread: Seahawks (4.5)
• Moneyline: Seahawks (-198); Panthers (+164)
• Over/under: 43

Bears at Chiefs odds

• Spread: Chiefs (-12.5)
• Moneyline: Chiefs (+600); Bears (+455)
• Over/under: 49

Cowboys at Cardinals odds

• Spread: Cowboys (-12.5)
• Moneyline: Cowboys (+600); Cardinals (+440)
• Over/under: 44

Steelers at Raiders odds

• Spread: Steelers (-1)
• Moneyline: Steelers (-115); Raiders (-105)
• Over/under: 44.5

Eagles at Buccaneers odds

• Spread: Eagles (-6.5)
• Moneyline: Eagles (-290); Buccaneers (+235)
• Over/under: 45

Rams at Bengals odds

• Spread: Bengals (-6.5)
• Moneyline: Bengals (-285); Rams (+230)
• Over/under: 46.5

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